Search Results - rig

PRT-060318 (PRT318, P142–76)

PRT-060318 (PRT318, P142–76) (CAS No.: 1194961-19-7), a potent and selective inhibitor of spleen tyrosine kinase (Syk; IC50 = 4 nM). It is selective, inhibiting 92% of Syk activity, while other kinases retain >70% activity, at...

JNJ-4796

JNJ-4796 (CAS No.: 2241664-16-2), an oral active fusion inhibitor of influenza virus, neutralizing influenza A group 1 viruses by inhibiting hemagglutinin (HA)-mediated fusion. >98% Purity. Synonyms: JNJ4796, fusion inhibitor, influenza virus inhibitor For Research Use Only.

DEL-22379

DEL-22379 (CAS No.: 181223-80-3), a potent and selective ERK Dimerization inhibitor. DEL-22379 inhibits ERK Dimerization without affecting ERK phosphorylation, forestalls tumorigenesis driven by RAS-ERK pathway oncogenes. Nearly 50% of human malignancies exhibit unregulated RAS-ERK...

RTA-408 (Omaveloxolone)

RTA-408 (CAS No.: 1474034-05-3), a Novel Synthetic Triterpenoid That Binds to Kelch-like ECH-associated Protein 1 (Keap1) and Attenuate Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Degradation. >99% Purity. Synonyms: Omaveloxolone, Nuclear Factor Erythroid 2-Related Factor 2, Nrf2,...

ND-646

ND-646 (CAS No.: 1434639-57-2), an Orally Bioavailable and Steric Inhibitor of Acetyl-CoA Carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for Recombinant hACC1 and hACC2, Respectively. >99% Purity. Synonyms: Acetyl-CoA Carboxylase, ACC For Research Use Only.

Etoposide phosphate (BMY-40481)

Etoposide Phosphate (BMY-40481) (CAS No.: 117091-64-2), potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands. Synonyms: topoisomerase II inhibitor, BMY-40481, BMY40481, BMY 40481 For Research Use Only.