Custom AAV production services including AAV plasmid vector construction, helper-free AAV packaging, AAV purification by iodixanol density gradient ultracentrifugation or column chromatography, AAV titration by qPCR. Multiple serotypes. High yield, high purity, high infectivity. Quality...
We provide the services of developing stable cell lines for: G-Protein Coupled Receptors (GPCR) of high pharmacological relevance; other cell-based assays such as ion channel and kinases (RTKs).
Fast stable cell line generation service for antibody production: development of suspension CHO stable cell lines for antibody production. No virus involved. DNA Transfection and stable cell line screening only.
Kinetic analysis is used to determine the affinity of an antibody to its soluble antigen using surface plasmon resonance (SPR) or biolayer interferometry (BLI), which can measure kon, koff, and kD. Association and dissociation are...
General procedure of the antibody sequence liability identification service: the antibody variable regions of both heavy chain (VH) and light chain (VL) are analyzed for liabilities including, but not limited to N-linked glycosylation, deamidation, isomerization,...
N-terminal Edman sequencing of proteins or peptides can be used to determine the N-terminal amino acid residues of purified protein samples in addition to cleavage sites, and to identify an unknown protein or confirm the...
Custom measurement of endotoxins levels in biological samples such as DNA and protein preparations.
A standard human Fcγ receptor panel binding assay in a high throughput format using the BLI platform. An FcRn binding assay to study pH-dependent interaction of antibody with the neonatal Fc-receptor (FcRn) in high throughput...
Reversed-phase chromatography (RP-HPLC) is an analytical technique that separates molecules on the basis of differences in their hydrophobicity.
