Phospho-Camk2a-T286 Rabbit mAb

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Phospho-Camk2a-T286 Rabbit mAb

$148.00$548.00

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$148.00$548.00

CAMKA; MRD53; MRT63; CaMKIIalpha; CaMKIINalpha

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Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Catalog No. AP1386
Product NamePhospho-Camk2a-T286 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms CAMKA; MRD53; MRT63; CaMKIIalpha; CaMKIINalpha
Gene Name CAMK2A
Protein Name CAMK2A
Uniprot/Swissprot ID Q9UQM7
Gene ID 815
Clone ARC57709
Clonality Monoclonal
Source/Host Rabbit
Reactivity Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.

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