Phospho-ATR-S428 Rabbit mAb
$148.00 – $548.00
FRP1; MEC1; SCKL; FCTCS; SCKL1
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| Catalog No. | AP1358 |
|---|---|
| Product Name | Phospho-ATR-S428 Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | FRP1; MEC1; SCKL; FCTCS; SCKL1 |
| Gene Name | ATR |
| Protein Name | ATR |
| Uniprot/Swissprot ID | Q13535 |
| Gene ID | 545 |
| Clone | ARC55118 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
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