OGDH Rabbit mAb
$148.00 – $548.00
E1k; E1o; KGD1; OGDC; AKGDH; OGDH2; OGDHD; OGDH-E1
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| Catalog No. | A22163 |
|---|---|
| Product Name | OGDH Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | E1k; E1o; KGD1; OGDC; AKGDH; OGDH2; OGDHD; OGDH-E1 |
| Gene Name | OGDH |
| Protein Name | OGDH |
| Uniprot/Swissprot ID | Q02218 |
| Gene ID | 4967 |
| Clone | ARC55379 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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