Nimotuzumab Biosimilar, Anti-human EGFR Monoclonal Antibody
$175.00 – $1,600.00
The cheapest research grade nimotuzumab biosimilar (anti-human EGFR monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in vitro and in vivo assays for studying biological pathways affected by nimotuzumab. The research grade nimotuzumab biosimilar protein is for research use only.
- Product Details
- Description
- Additional information
- More Offers
| Catalog No. | C056P |
|---|---|
| Product Name | Nimotuzumab Biosimilar, Anti-human EGFR Monoclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Source/Host | The anti-human EGFR monoclonal antibody nimotuzumab biosimilar was produced in mammalian cells. |
| Specificity/Sensitivity | The research grade nimotuzumab biosimilar specifically binds to the human epidermal growth factor receptor (EGFR). |
| Applications | ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by nimotuzumab. |
| Form Of Antibody | 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives. |
| Endotoxin | < 0.1 EU per 1 ug of the protein by the LAL method. |
| Purity | >95% by SDS-PAGE under reducing conditions and HPLC. |
| Shipping | The research grade nimotuzumab biosimilar is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card. |
Description
C009P: Nimotuzumab Biosimilar (Research Grade), Anti-human Epidermal Growth Factor Receptor (EGFR) Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Background
Nimotuzumab Biosimilar uses the same protein sequences as the therapeutic antibody nimotuzumab.
Like cetuximab, nimotuzumab is a humanized monoclonal antibody that binds to the epidermal growth factor receptor (EGFR), a signalling protein that normally controls cell division. In some cancers, this receptor is altered to cause uncontrolled cell division, a hallmark of cancer. These monoclonal antibodies block EGFR and stop the uncontrolled cell division.
It has a humanized human-mouse h-R3 heavy chain and a humanized human-mouse h-R3 κ-chain.
Nimotuzumab binds with optimal affinity and high specificity to the extracellular region of EGFR (epidermal growth factor receptor). This results in a blockade of ligand binding and receptor activation. Epidermal growth factor receptor (EGFR) is a key target in the development of cancer therapeutics. EGFR-targeting drugs have been shown to improve response when used with conventional treatments such as radiation therapy and chemotherapy.
Syd Labs also provides the following anti-EGFR antibody biosimilar proteins:
Cetuximab Biosimilar, research grade, anti-human EGFR monoclonal antibody
Cetuximab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant
Matuzumab Biosimilar, research grade, anti-human EGFR monoclonal antibody
Panitumumab Biosimilar, research grade, anti-human EGFR monoclonal antibody
Panitumumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant
Zalutumumab Biosimilar, research grade, anti-human EGFR monoclonal antibody
Syd Labs provides a number of research grade antibody biosimilar proteins with competitive prices starting from $3/mg. Syd Labs also introduces mutations to the antibody biosimilars including engineering or switching the isotypes or Fc engineering, such as Fc silent.
Syd Labs also produces the in vivo grade isotype control antibodies. Some customers purchase them for in vitro assays such as flow cytometry or immunohistochemistry (IHC) because the prices are too good if compared to those research reagents of antibody isotype controls . Syd Labs provides the following in vivo grade recombinant human IgG1 kappa isotype control antibody proteins and mutants:
In vivo grade recombinant human IgG1 isotype control antibody
In vivo grade recombinant human IgG1 Fc protein
In vivo grade recombinant human IgG1-D265A isotype control antibody
In vivo grade recombinant human IgG1-N297A isotype control antibody
In vivo grade recombinant human IgG1-D265A N297A isotype control antibody
In vivo grade recombinant human IgG1-L234A L235A P329G (LALAPG) isotype control antibody
Frequent questions related to “research grade nimotuzumab biosimilar, anti-human EGFR monoclonal antibody”:
Does nimotuzumab bind mouse EGFR?
Is nimotuzumab humanized?
What is the mechanism of action for nimotuzumab?
Popular searches related to “research grade nimotuzumab biosimilar, anti-human EGFR monoclonal antibody”:
nimotuzumab monoclonal antibody
nimotuzumab purchase
nimotuzumab mechanism of action
nimotuzumab price
EGFR mouse cell line
epidermal growth factor receptor
Nimotuzumab Biosimilar Research Grade
EGFR
Additional information
| Size | 1 mg, 20 mg, 5 mg |
|---|