Interferon alpha 2 (IFN-α2) Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Interferon alpha 2 (IFN-α2) Rabbit mAb

$148.00$548.00

In stock

$148.00$548.00

IFNA; IFNA2B; leIF A; IFN-alphaA; IFN-alpha-2

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Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Catalog No. A21263
Product NameInterferon alpha 2 (IFN-α2) Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms IFNA; IFNA2B; leIF A; IFN-alphaA; IFN-alpha-2
Gene Name IFNA2
Protein Name IFNA2
Uniprot/Swissprot ID P01563
Gene ID 3440
Clone ARC53291
Clonality Monoclonal
Source/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach.

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