Human PD-1/PDCD1 Protein (PD1-HM301)
$135.00 – $450.00
KACTUS Biosystems Human PD-1/PDCD1 Protein (PD1-HM301) (catalog No. PD1-HM301) is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Leu25-Gln167.
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| Catalog No. | PD1-HM301 |
|---|---|
| Product Name | Human PD-1/PDCD1 Protein (PD1-HM301) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | PDCD1; PD1; CD279; SLEB2; PD-1 |
| Species | Human |
| Source | HEK293 |
| Accession | Q15116-1 |
| Product Tag | C-mFc |
| Biotinylated | no |
| Exact Sequence | Leu25-Gln167 |
| Molecular Weight | The protein has a predicted MW of 41.6 kDa. Due to glycosylation, the protein migrates to 64-68 kDa based on Tris-Bis PAGE result. |
| Activity | Immobilized Human PD-1, mFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human PD-L1, hFc Tag with the EC50 of 0.93ug/ml determined by ELISA (QC Test). See testing image for detail. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PD1-HM301: Human PD-1/PDCD1 Protein (PD1-HM301)
Recombinant Human PD-1/PDCD1 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Leu25-Gln167.
Programmed Death-1 receptor (PD-1), also known as CD279, is type I transmembrane protein belonging to the CD28 family of immune regulatory receptors.PD1 is a inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell receptor (TCR) engagement, PDCD1 associates with CD3-TCR in the immunological synapse and directly inhibits T-cell activation.
Please remember our product information: Human PD-1/PDCD1 Protein (PD1-HM301) catalog number: PD1-HM301 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |