Biotinylated Human PD-1/PDCD1 Protein (PD1-HM401B)

Catalog No.	PD1-HM401B
Product Name	Biotinylated Human PD-1/PDCD1 Protein (PD1-HM401B)
Supplier Name	KACTUS Biosystems
Brand Name	KACTUS Biosystems
Synonyms	PDCD1; PD1; CD279; SLEB2; PD-1
Species	Human
Source	HEK293
Accession	Q15116-1
Product Tag	C-His-Avi
Biotinylated	yes
Exact Sequence	Leu25-Gln167
Molecular Weight	The protein has a predicted MW of 18.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Biotinylated Human PD-1, His Tag at 1ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Human PD-L1, hFc Tag with the EC50 of 73.1ng/ml determined by ELISA (QC Test). The affinity constant of 2.356 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Form	Lyophilized
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per μg by the LAL method.
Shipping	Shipped at ambient temperature.
Stability & Storage	'-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PD1-HM401B: Biotinylated Human PD-1/PDCD1 Protein (PD1-HM401B)

Recombinant Biotinylated Human PD-1/PDCD1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Leu25-Gln167.

Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system’s response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.

Please remember our product information: Biotinylated Human PD-1/PDCD1 Protein (PD1-HM401B) catalog number: PD1-HM401B KACTUS Biosystems

Additional information

Ship from Country	USA
Size	100 ug, 500 ug

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