Human ALK-1/ACVRL1 Protein (ALK-HM101)
$216.00 – $720.00
KACTUS Biosystems Human ALK-1/ACVRL1 Protein (ALK-HM101) (catalog No. ALK-HM101) is expressed from HEK293 with His tag at the C-Terminus.It contains Asp22-Gln118.
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Catalog No. | ALK-HM101 |
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Product Name | Human ALK-1/ACVRL1 Protein (ALK-HM101) |
Supplier Name | KACTUS Biosystems |
Brand Name | KACTUS Biosystems |
Synonyms | ACVRLK1; ORW2; ALK1; ALK-1; EC 2.7.11; HHT; HHT2; SKR3; TSR-I; ACVRL1 |
Species | Human |
Source | HEK293 |
Accession | P37023 |
Product Tag | C-His |
Biotinylated | no |
Exact Sequence | Asp22-Gln118 |
Molecular Weight | The protein has a predicted MW of 11.5 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result. |
Form | Lyophilized |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per μg by the LAL method. |
Shipping | Shipped at ambient temperature. |
Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.;-20 to -80°C for 3-6 months in unopened state after reconstitution.;2-8°C for 2-7 days after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
ALK-HM101: Human ALK-1/ACVRL1 Protein (ALK-HM101)
Activin receptor-like kinase 1 (ALK1)-mediated endothelial cell signalling in response to bone morphogenetic protein 9 (BMP9) and BMP10 is of significant importance in cardiovascular disease and cancer. Structural analyses reveal a tripartite recognition mechanism that defines BMP9 and BMP10 specificity for ALK1, and predict that crossveinless 2 is not an inhibitor of BMP9, which is confirmed by experimental evidence.
Please remember our product information: Human ALK-1/ACVRL1 Protein (ALK-HM101) catalog number: ALK-HM101 KACTUS Biosystems
Additional information
Ship from Country | USA |
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Size | 100 ug, 500 ug |