Fascin/FSCN1 Rabbit mAb (A9566)
$148.00 – $548.00
Abclonal Fascin/FSCN1 Rabbit mAb (Catalog Number: A9566) encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions.
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| Catalog No. | A9566 |
|---|---|
| Product Name | Fascin/FSCN1 Rabbit mAb (A9566) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | HSN; SNL; p55; FAN1 |
| Gene Name | FSCN1 |
| Protein Name | FSCN1 |
| Uniprot/Swissprot ID | Q16658 |
| Gene ID | 6624 |
| Clone | ARC1638 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A9566: Fascin/FSCN1 Rabbit mAb
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin’s lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.
Immunogen Information about Fascin/FSCN1 Rabbit mAb (A9566)
Immunogen：Recombinant fusion protein containing a sequence corresponding to amino acids 249-362 of human Fascin/FSCN1 (Q16658).
Sequence：GKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWRDRRITLRASNGKFVTSKKNGQ
Gene ID：6624
Swiss prot：Q16658
Synonyms：HSN; SNL; p55; FAN1; Fascin/FSCN1
Calculated MW：55kDa
Observed MW：54kDa
Images of Fascin/FSCN1 Rabbit mAb (A9566)
Western blot analysis of extracts of various cell lines, using Fascin/FSCN1 Rabbit mAb (A9566) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 1s.
Immunohistochemistry analysis of paraffin-embedded Human anaplastic large cell lymphoma using Fascin/FSCN1 Rabbit mAb (A9566) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded Human Hodgkin lymphoma using Fascin/FSCN1 Rabbit mAb (A9566) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded human tonsil using Fascin/FSCN1 Rabbit mAb (A9566) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Please remember our product information: Fascin/FSCN1 Rabbit mAb (Catalog Number: A9566) Abclonal
