DcR1 / CD263 Rabbit mAb
$148.00 – $548.00
LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR
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| Catalog No. | A23554 |
|---|---|
| Product Name | DcR1 / CD263 Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR |
| Gene Name | TNFRSF10C |
| Protein Name | TNFRSF10C |
| Uniprot/Swissprot ID | O14798 |
| Gene ID | 8794 |
| Clone | ARC3107 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
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