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Description
Background Information:
A potent and selective HDAC6 inhibitor, – with 3700-fold selectivity over HDAC1 (IC50 1.4 nM for HDAC6 vs 5180 nM for HDAC1).
Reference:
1. K. V. Bulter, et al., Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A. J. Am. Chem. Soc., (2010) 132 (31), pp 10842–10846.
2. Our in-house head-to-head assay for ChemieTek’s three HDAC6 inhibitors, Tubacin, Tubastatin A and Compound 7, has yielded IC50s of 5, 7 and 4 nM, respectively.
APIM050322: COMPOUND 7 (HCL SALT)
CAS No.: 1252003-13-6.
Molecular Formula: C20H21N3O2?HCl ? 0.4H2O.
Molecular Weight: 379.1.
Purity: >99% (HPLC).
QC: HPLC, MS, 1HNMR, and Quantitative Elemental Analysis Report.
Solubility: Soluble in DMSO, water.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 10 mg, 100 mg, 200 mg, 50 mg |
