CDKN1C/p57 Kip2 Rabbit mAb
$148.00 – $548.00
BWS; WBS; p57; BWCR; KIP2; p57Kip2
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| Catalog No. | A6843 |
|---|---|
| Product Name | CDKN1C/p57 Kip2 Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | BWS; WBS; p57; BWCR; KIP2; p57Kip2 |
| Gene Name | CDKN1C |
| Protein Name | CDKN1C |
| Uniprot/Swissprot ID | P49918 |
| Gene ID | 1028 |
| Clone | ARC1424 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
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