CDKN1B/p27KIP1 Rabbit mAb (A19095)
$148.00 – $548.00
Abclonal CDKN1B/p27KIP1 Rabbit mAb (Catalog Number: A19095) encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21.
- Details & Specifications
- References
- More Offers
| Catalog No. | A19095 |
|---|---|
| Product Name | CDKN1B/p27KIP1 Rabbit mAb (A19095) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | KIP1; MEN4; CDKN4; MEN1B; P27KIP1 |
| Gene Name | CDKN1B |
| Protein Name | CDKN1B |
| Uniprot/Swissprot ID | P46527 |
| Gene ID | 1027 |
| Clone | ARC0455 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A19095: CDKN1B/p27KIP1 Rabbit mAb
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).
Immunogen Information about CDKN1B/p27KIP1 Rabbit mAb (A19095)
Immunogen：A synthetic peptide corresponding to a sequence within amino acids 99-198 of human CDKN1B/p27KIP1 (P46527).
Sequence：CKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
Gene ID：1027
Swiss prot：P46527
Synonyms：KIP1; MEN4; CDKN4; MEN1B; P27KIP1; CDKN1B/p27KIP1
Calculated MW：22kDa
Observed MW：22kDa
Images of CDKN1B/p27KIP1 Rabbit mAb (A19095)
Western blot analysis of extracts of various cell lines, using CDKN1B/p27KIP1 antibody (A19095) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit (RM00021).
Exposure time: 3min.
Immunohistochemistry analysis of paraffin-embedded human brain using CDKN1B/p27KIP1 Rabbit mAb (A19095) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded human breast cancer using CDKN1B/p27KIP1 Rabbit mAb (A19095) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded Human lung adenocarcinoma using CDKN1B/p27KIP1 Rabbit mAb (A19095) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded human lung squamous carcinoma tissue using CDKN1B/p27KIP1 Rabbit mAb (A19095) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded human placenta using CDKN1B/p27KIP1 Rabbit mAb (A19095) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded human spleen using CDKN1B/p27KIP1 Rabbit mAb (A19095) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded human thyroid using CDKN1B/p27KIP1 Rabbit mAb (A19095) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded human tonsil using CDKN1B/p27KIP1 Rabbit mAb (A19095) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded rat ovary using CDKN1B/p27KIP1 Rabbit mAb (A19095) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Please remember our product information: CDKN1B/p27KIP1 Rabbit mAb (Catalog Number: A19095) Abclonal
