Anti-Mouse CD18 Antibody (Clone:M18/2.a.12.7) | PA007583.r2a

Recombinant Anti-mouse CD18 Monoclonal Antibody (M18/2.a.12.7), In Vivo PA007583.r2a Syd Labs

Anti-Mouse CD18 Antibody (Clone:M18/2.a.12.7) | PA007583.r2a

$150.00 – $900.00

In stock

$150.00 – $900.00

Recombinant rat IgG2a isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.

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Catalog No. PA007583.r2a
Product Name In Vivo Grade Recombinant Anti-mouse CD18 Monoclonal Antibody (Clone: M18/2.a.12.7), Rat IgG2a Kappa
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms Integrin beta-2 (ITGB2), 2E6, LAD, Lfa1, MF17, LCAMB, TNFR2-RP, TNFRrp, Tnfbr
Clone M18/2.a.12.7.
Isotype Rat IgG2a Kappa.
Source/Host The anti-mouse CD18 monoclonal antibody (clone: M18/2.a.12.7) was produced in mammalian cells.
Specificity/Sensitivity The in vivo grade recombinant rat monoclonal antibody (clone: M18/2.a.12.7) specifically binds to mouse CD18.
Applications ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD18 protein.
Form Of Antibody 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin < 1 EU per 1 mg of the protein by the LAL method.
Purity >95% by SDS-PAGE under reducing conditions and HPLC.
Shipping The in vivo grade recombinant anti-mouse CD18 monoclonal antibody of clone M18/2.a.12.7 is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
Note Recombinant rat IgG2a isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Order Offline Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card.

Description

PA007583.r2a: In Vivo Grade Recombinant Anti-mouse CD18 Monoclonal Antibody (Clone: M18/2.a.12.7), Rat IgG2a Kappa

Recombinant Rat IgG2a Monoclonal Antibody.

References of Anti-mouse CD18 Monoclonal Antibody (Clone: M18/2.a.12.7)

1. Anti-CD18 monoclonal antibody slows reinnervation after nerve injury.
Cotman JD, et al.J Hand Surg Am. 2003 Nov;28(6):1021-7. PMID: 14568010
“Rats were treated with anti-mouse CD18 antibody (M18/2 clone) intraperitoneally to block leukocyte adhesion in vivo. Anti-mouse CD18 administration delayed axonal regeneration in the sciatic nerve model. In vivo CD18 blockade reduced macrophage infiltration at the injury site. Functional recovery assessed by walking track analysis was slowed post-anti-mouse CD18. Nerve histology showed decreased myelin formation in anti-mouse CD18 cohorts.”

For more technical references or data sheets regarding the Recombinant Anti-mouse CD18 Monoclonal Antibody (Clone: M18/2.a.12.7) formats, please contact our scientific support team at message@sydlabs.com.

In Vivo Grade Recombinant Anti-mouse CD18 Monoclonal Antibody (Clone: M18/2.a.12.7), Rat IgG2a Kappa from: In Vivo Grade Recombinant Anti-mouse CD18 Monoclonal Antibody (Clone: M18/2.a.12.7), Rat IgG2a Kappa: PA007583.r2a