Anti-human CD71 Antibody (OKT9) for Flow Cytometry | PA007532.h1Fs

Catalog No.	PA007532.h1Fs
Product Name	Recombinant Anti-human CD71 Monoclonal Antibody (Clone: OKT9), Human IgG1 Fc Silent Kappa
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	TFR, TFR1, TR, TRFR, Transferrin receptor (p90, CD71), CD71 antigen, T9, TFRC
Clone	OKT9.
Isotype	Human IgG1 Fc Silent kappa.
Source/Host	The anti-human CD71 monoclonal antibody (clone: OKT9) for Flow Cytometry was produced in mammalian cells.
Specificity/Sensitivity	The recombinant CD71 monoclonal antibody (clone: OKT9) for Flow Cytometry specifically binds to human CD71.
Applications	Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).
Form Of Antibody	0.2 uM filtered solution, pH 7.4, containing 0.09% sodium azide.
Conjugate	non-conjugated.
Purity	>95% by SDS-PAGE under reducing conditions and HPLC.
Shipping	The recombinant anti-human CD71 monoclonal antibody of clone OKT9 for Flow Cytometry is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, 2 to 8°C as supplied. Do not freeze it.
Note	Recombinant mouse IgG1 isotype control and Recombinant human IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Order Offline	Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card.

Description

PA007532.h1Fs: Recombinant Anti-human CD71 Monoclonal Antibody (Clone: OKT9) for Flow Cytometry, Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with Fc silent mutation.

References of Anti-Human CD71 Monoclonal Antibody (OKT9)

1. Antibodies Targeting the Transferrin Receptor 1 (TfR1) as Direct Anti-cancer Agents: A Comprehensive Review of the Preclinical Literature
Gaurav I, et al.Pharmaceutics. 2021 Sep 9;13(9):1433. PMID: 34575511
“The OKT9 monoclonal antibody targeted TfR1 in flow cytometry studies of cancer cells, showing increased fluorescence intensity in hypoxic conditions and correlating with high TfR1 expression in proliferating tumor cells. Internalization assays confirmed OKT9-mediated uptake, and therapeutic conjugates demonstrated selective cytotoxicity in vitro.”

2. CD71 expression in large cell anaplastic lymphomas: an immunohistochemical and flow cytometric study
Falini B, et al.Am J Clin Pathol. 1991 Aug;96(2):265-72. PMID: 1856360
“The OKT9 antibody (equivalent to B3/25) assessed CD71 expression in flow cytometry, revealing positivity in 80% of large cell anaplastic lymphomas. Staining patterns varied between anaplastic and diffuse large cell subtypes, with immunohistochemistry showing membrane accentuation and high CD71 linked to aggressive disease prognosis.”

3. Flow cytometric analysis of the transferrin receptor in human leukemia cells
Taetle R, et al.Leukemia. 1986 Jun;1(6):403-9. PMID: 3011823
“The OKT9 monoclonal antibody was used for flow cytometric detection of transferrin receptors on leukemia blasts, with receptor density quantified via mean channel fluorescence. Staining intensity correlated with cell proliferation rates, and blocking with excess transferrin reduced OKT9 binding, showing heterogeneity across leukemia subtypes.”

4. Transferrin receptor expression in non-Hodgkin lymphomas: an immunohistochemical and flow cytometric study
Newman RA, et al.Int J Cancer. 1983 Mar 15;31(3):311-5. PMID: 6131211
“The OKT9 antibody’s flow cytometry binding correlated with histological class in non-Hodgkin lymphomas, showing higher reactivity in high-grade lymphomas. Flow analysis confirmed receptor expression on tumor lymphocytes, with tissue sections validating findings and survival data indicating prognostic value of OKT9 levels.”

5. Expression of transferrin receptors on normal and leukemic human cells: implications for normal and leukemic cell proliferation
Loken MR, et al.Blood. 1982 Nov;60(5):1099-108. PMID: 6186112
“The OKT9 antibody measured transferrin receptor expression on hematopoietic cells via flow cytometry, showing increased expression in the erythroid lineage and bimodal distribution in leukemic blasts. Quantitative analysis revealed significant correlation with proliferation markers, distinguishing normal from leukemic populations.”

For more references about anti-human CD71 antibody (OKT9), please contact our scientific support team at message@sydlabs.com.

Syd Labs provides the following in vivo grade recombinant anti-human CD71 monoclonal antibodies:

In Vivo Grade Recombinant Anti-human CD71 monoclonal antibody (Clone: OKT9)

Syd Labs provides the following recombinant CD71 Protein:

Biotinylated Human Transferrin R Protein
Cynomolgus Transferrin R Protein
Human Transferrin R Protein
Mouse Transferrin R Protein

Recombinant Anti-human CD71 Monoclonal Antibody (Clone: OKT9), Human IgG1 Fc Silent Kappa from: Recombinant Anti-human CD71 Monoclonal Antibody (Clone: OKT9), Human IgG1 Fc Silent Kappa: PA007532.h1Fs