Anti-Human CD235a (Glycophorin A type M) Antibody (Clone:6A7M) | PA007607.m1
$150.00 – $900.00
Recombinant mouse IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
- Details & Specifications
- References
| Catalog No. | PA007607.m1 |
|---|---|
| Product Name | In Vivo Grade Recombinant Anti-human CD235a (Glycophorin A type M) Monoclonal Antibody (Clone: 6A7M), Mouse IgG1 Kappa |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | PAS-2, Sialoglycoprotein alpha, MN sialoglycoprotein, Glycophorin A, MNS blood group, GYPA |
| Clone | 6A7M. |
| Isotype | Mouse IgG1 Kappa. |
| Source/Host | The anti-human CD235a (Glycophorin A type M) monoclonal antibody (clone: 6A7M) was produced in mammalian cells. |
| Specificity/Sensitivity | The in vivo grade recombinant mouse monoclonal antibody (clone: 6A7M) specifically binds to human CD235a (Glycophorin A type M). |
| Applications | ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human CD235a (Glycophorin A type M) protein. |
| Form Of Antibody | 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives. |
| Endotoxin | < 1 EU per 1 mg of the protein by the LAL method. |
| Purity | >95% by SDS-PAGE under reducing conditions and HPLC. |
| Shipping | The in vivo grade recombinant anti-human CD235a (Glycophorin A type M) monoclonal antibody of clone 6A7M is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |
| Note | Recombinant mouse IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card. |
Description
PA007607.m1:In Vivo Grade Recombinant Anti-human CD235a (Glycophorin A type M) Monoclonal Antibody (Clone: 6A7M), Mouse IgG1 Kappa
Recombinant Mouse IgG1 Monoclonal Antibody.
References of Anti-Human CD235a (Glycophorin A type M) Monoclonal Antibody (Clone: 6A7M)
1. CD71+ Erythroid Cells Exacerbate HIV-1 Susceptibility, Mediate trans-Infection, and Harbor Infective Viral Particles.
Namdar A, et al.mBio. 2019 Nov 26;10(6):e02767-19. doi: 10.1128/mBio.02767-19. PMID: 31772057
“In contrast, we observed CECs bind to HIV-1 via CD235a and subsequently transfer the virus to uninfected CD4+ T cells, which can be partially blocked by the anti-CD235a antibody. …They coexpress the transferrin receptor (CD71) and the erythroid lineage marker (TER119) in mice but CD71 and CD235a in humans. …In contrast, HIV-1 binds to CD235a, and thus CECs cannot only trans-infect uninfected CD4+ T cells but also harbor infective virions in the presence of antiretroviral therapy (ART) drugs. …Representative plots (B) and cumulative data (C) showing HIV trans-infection from RBCs of CD4+ T cells in the absence or presence of anti-CD235a antibody. …More importantly, we observed more efficient interaction of HIV with CD235a on CECs compared to RBCs.”
For more technical references or data sheets regarding the Recombinant Anti-Human CD235a (Glycophorin A type M) Monoclonal Antibody (Clone: 6A7M) formats, please contact our scientific support team at message@sydlabs.com.
In Vivo Grade Recombinant Anti-human CD235a (Glycophorin A type M) Monoclonal Antibody (Clone: 6A7M), Mouse IgG1 Kappa from: In Vivo Grade Recombinant Anti-human CD235a (Glycophorin A type M) Monoclonal Antibody (Clone: 6A7M), Mouse IgG1 Kappa: PA007607.m1
