ABflo® 647 Rabbit anti-Human TNF-α mAb (A22782)
$218.00 – $568.00
Abclonal ABflo® 647 Rabbit anti-Human TNF-α mAb (Catalog Number: A22782) encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily.
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| Catalog No. | A22782 |
|---|---|
| Product Name | ABflo® 647 Rabbit anti-Human TNF-α mAb (A22782) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha |
| Gene Name | TNF |
| Protein Name | TNF |
| Uniprot/Swissprot ID | P01375 |
| Entrez GeneID | 7124 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | FC |
| Reactivity | Human |
| Conjugate | ABflo® 647. Ex:656nm. Em:670nm. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A22782: ABflo® 647 Rabbit anti-Human TNF-α mAb
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Immunogen Information about ABflo® 647 Rabbit anti-Human TNF-α mAb (A22782)
Immunogen：Recombinant fusion protein containing a sequence corresponding to amino acids 77-233 of human TNF-α (NP_002344.2).
Sequence：VRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
Gene ID：7124
Swiss prot：P01375
Synonyms：DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha
Calculated MW：26kDa
Observed MW：
Images of ABflo® 647 Rabbit anti-Human TNF-α mAb (A22782)
Flow cytometry:1X10^6 293F cells (negative control, Left) and 293F(Transfection, right) cells were intracellularly-stained with ABflo® 647 Rabbit anti-Human TNF-α mAb(A22782, 5 μl/Test, orange line) or ABflo® 647 Rabbit IgG isotype control (A22070, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry:1X10^6 293F(Transfection) cells were intracellularly-stained with ABflo® 647 Rabbit IgG isotype control (A22070, 5 μl/Test, left) or ABflo® 647 Rabbit anti-Human TNF-α mAb(A22782, 5 μl/Test, right).
Flow cytometry:1X10^6 Human PBMC were intracellularly-stained with ABflo® 647 Rabbit anti-Human TNF-α mAb(A22782, 5 μl/Test, orange line) or ABflo® 647 Rabbit IgG isotype control (A22070, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry:1X10^6 Human PBMC were intracellularly-stained with ABflo® 647 Rabbit IgG isotype control (A22070, 5 μl/Test, left) or ABflo® 647 Rabbit anti-Human TNF-α mAb(A22782, 5 μl/Test, right).
Please remember our product information: ABflo® 647 Rabbit anti-Human TNF-α mAb (Catalog Number: A22782) Abclonal
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 μg, 25 μg, 50 μg |