ABflo® 488 Rabbit anti-Human CD25 mAb (A23169)
$218.00 – $568.00
Abclonal ABflo® 488 Rabbit anti-Human CD25 mAb (Catalog Number: A23169) The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor.
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| Catalog No. | A23169 |
|---|---|
| Product Name | ABflo® 488 Rabbit anti-Human CD25 mAb (A23169) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | p55; CD25; IL2R; IMD41; TCGFR; IDDM10 |
| Gene Name | IL2RA |
| Protein Name | IL2RA |
| Uniprot/Swissprot ID | P01589 |
| Gene ID | 3559 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human |
| Conjugate | ABflo® 488. Ex:491nm. Em:516nm. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A23169: ABflo® 488 Rabbit anti-Human CD25 mAb
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk.
Immunogen Information about ABflo® 488 Rabbit anti-Human CD25 mAb (A23169)
Immunogen：Recombinant fusion protein containing a sequence corresponding to amino acids 22-213 of human CD25 (NP_000408.1).
Sequence：ELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQASLPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQPQLICTGEMETSQFPGEEKPQASPEGRPESETSC
Gene ID：3559
Swiss prot：P01589
Synonyms：p55; CD25; IL2R; IMD41; TCGFR; IDDM10
Calculated MW：31kDa
Observed MW：Refer to figures
Images of ABflo® 488 Rabbit anti-Human CD25 mAb (A23169)
Flow cytometry:1X10^6 293F cells (negative control, Left) and 293F(Transfection, right) cells were surface-stained with ABflo® 488 Rabbit anti-Human CD25 mAb(A23169, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry:1X10^6 293F(Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Human CD25 mAb(A23169, 5 μl/Test, right).
Please remember our product information: ABflo® 488 Rabbit anti-Human CD25 mAb (Catalog Number: A23169) Abclonal
