Abciximab Biosimilar, Anti-human Glycoprotein IIb/IIIa Receptor Monoclonal Antibody

antibodies

Abciximab Biosimilar, Anti-human Glycoprotein IIb/IIIa Receptor Monoclonal Antibody

$250.00$2,000.00

In stock

$250.00$2,000.00

Abciximab Biosimilar, Glycoprotein IIb/IIIa Receptor Monoclonal Antibody. The research grade abciximab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available.

SKU: C039P
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Catalog No. C039P
Product NameAbciximab Biosimilar, Anti-human Glycoprotein IIb/IIIa Receptor Monoclonal Antibody
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Summary Recombinant Humanized IgG1 Monoclonal Antibody.
Source/Host The anti-human Glycoprotein IIb/IIIa receptor monoclonal antibody abciximab biosimilar was produced in mammalian cells.
Specificity/Sensitivity The research grade abciximab biosimilar specifically binds to the human Glycoprotein IIb and IIIa.
Applications ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by abciximab.
Form Of Antibody 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin <1 EU/mg of the protein by the LAL method.
Purity >95% by SDS-PAGE under reducing conditions and HPLC.
Shipping The research grade abciximab biosimilar is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
Note The research grade abciximab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available.
Order Offline Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card.

Description

C039P: Abciximab Biosimilar, Anti-human Glycoprotein IIb/IIIa Receptor Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.

Background

Abciximab Biosimilar uses the same protein sequences as the therapeutic antibody abciximab.

Abciximab, a glycoprotein IIb/IIIa receptor antagonist, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking together and causing thrombus (blood clot) formation within the coronary artery. It is a glycoprotein IIb/IIIa inhibitor.

While abciximab has a short plasma half-life, due to its strong affinity for its receptor on the platelets, it may occupy some receptors for weeks. In practice, platelet aggregation gradually returns to normal about 96 to 120 hours after discontinuation of the drug. Abciximab is made from the Fab fragments of an immunoglobulin that targets the glycoprotein IIb/IIIa receptor on the platelet membrane.

Syd Labs also provides the following research grade antibody biosimilar proteins:
Bevacizumab Biosimilar, research grade (VEGF-A)
Ranibizumab Biosimilar, research grade (VEGF-A, Fab produced in E. coli)
Cetuximab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Panitumumab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Trastuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Pertuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Infliximab biosimilar, research grade (TNF alpha)
Adalimumab biosimilar, research grade (TNF alpha)
Rituximab biosimilar, research grade (CD20)
Denosumab biosimilar, research grade (RANKL, RANK ligand, OPGL, TNFSF11, CD254, TRANCE, ODF)
Palivizumab Biosimilar, research grade (RSV)
Omalizumab biosimilar, research grade (IgE)
Eculizumab biosimilar, research grade (C5)

Please remember our product information: Abciximab Biosimilar, Glycoprotein IIb/IIIa Receptor Monoclonal Antibody: C039P Syd Labs

Additional information

Size

1 mg, 20 mg, 5 mg

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