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Description
Background Information:
A-769662 is a novel small molecule activator of AMP-activated protein kinase (AMPK).
Reference:
1. Cool, B., et al, Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cell Met. 3, 403 (2006).
2. Sanders, M., et al, Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family, J.Biol.Chem. 282, 32539 (2007).3. Scott, J., et al, Thienopyridone drugs are selective activators of AMP-activated protein kinase β1-containing complexes, Chem.Biol. 15, 1220 (2008).
APIM050070: A-769662
CAS No.: 844499-71-4.
Molecular Formula: C20H12N2O3S.
Molecular Weight: 360.39.
Purity: >99% (HPLC at 254 nm), >98.5% (HPLC at 214nm).
QC: 1HNMR, HPLC.
Solubility: Soluble in DMSO (200 mM) and Ethanol (to 25 mM).
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 10 mg, 100 mg, 200 mg, 50 mg |
