VE-822 (BERZOSERTIB)

Background Information:

VE-822 (Berzosertib) (M6620) is a potent and selective ATR Kinase
inhibitor with a Ki value of 0.2 nM, highly selective over
closely-related ATM Kinase (Ki=34 nM, >150 fold selectvity), DNA-PK
(Ki >4 uM) and mTOR (Ki >1 uM).

APIM050254: VE-822 (BERZOSERTIB)

CAS No.: 1232416-25-9.
Molecular Formula: C₂₄H₂₅N₅O₃S.
Molecular Weight: 463.6.
Purity: >99.5% (HPLC at 214 and 254 nm).
QC: HPLC-MS, ¹HNMR, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.