TG100-115

Background Information:

A PI3K P110 ?/δ isoform-selective inhibitor with IC50 values (nM) of
1300, 1200, 83 and 235 for p110α, p110β, P110 ?, and P110δ isoforms,
respectively.

Reference:

1. J Med Chem. 50: 4279-94 (2007).
2. Proc Natl Acad Sci U S A. 103: 19866-71 (2006).

APIM050246: TG100-115

CAS No.: 677297-51-7.
Molecular Formula: C₁₈H₁₄N₆O_2.
Molecular Weight: 346.34.
Purity: >99% (HPLC).
QC: LC/MS, ¹HNMR.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.