TFE3 Rabbit mAb (A0548)
$148.00 – $548.00
Abclonal TFE3 Rabbit mAb (Catalog Number: A0548) encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes.
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| Catalog No. | A0548 |
|---|---|
| Product Name | TFE3 Rabbit mAb (A0548) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | TFEA; RCCP2; RCCX1; MRXSPF; bHLHe33 |
| Gene Name | TFE3 |
| Protein Name | TFE3 |
| Uniprot/Swissprot ID | P19532 |
| Entrez GeneID | 7030 |
| Clone | ARC1829 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | WB, IHC-P |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A0548: TFE3 Rabbit mAb
This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.
Immunogen Information about TFE3 Rabbit mAb (A0548)
Immunogen：Recombinant fusion protein containing a sequence corresponding to amino acids 191-440 of human TFE3 (P19532).
Sequence：LQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLP
Gene ID：7030
Swiss prot：P19532
Synonyms：TFEA; RCCP2; RCCX1; MRXSPF; bHLHe33; TFE3
Calculated MW：62kDa
Observed MW：70kDa
Images of TFE3 Rabbit mAb (A0548)
Western blot analysis of extracts of various cell lines, using TFE3 Rabbit mAb (A0548) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.
Western blot analysis of extracts of HeLa cells, using TFE3 Rabbit mAb (A0548) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.
Immunohistochemistry analysis of paraffin-embedded Human acinar soft tissue sarcoma using TFE3 antibody (A0548) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Please remember our product information: TFE3 Rabbit mAb (Catalog Number: A0548) Abclonal
Additional information
| Ship from Country | USA |
|---|---|
| Size | 20 ul, 100 ul, 200 ul, 50 ul |