SARS PLpro/papain-like protease Protein (SAR-VE1PL)
$135.00 – $450.00
KACTUS Biosystems SARS PLpro/papain-like protease Protein (SAR-VE1PL) (catalog No. SAR-VE1PL) is expressed from E.coil with His tag and Avi tag at the N-Terminus.It contains Glu1-Ile314.
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| Catalog No. | SAR-VE1PL |
|---|---|
| Product Name | SARS PLpro/papain-like protease Protein (SAR-VE1PL) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | Replicase polyprotein 1a; pp1a; nsp1; PL2-PRO; PL-PRO; Papain-like Protease; Plpro |
| Species | SARS |
| Source | E.coli |
| Accession | P0C6U8 |
| Product Tag | N-His-Avi |
| Biotinylated | no |
| Exact Sequence | Glu1-Ile314 |
| Molecular Weight | The protein has a predicted MW of 38.6 kDa same as Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in 20mM Tris, 100mM NaCl, 10% Glycerol (pH 7.8). |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
SAR-VE1PL: SARS PLpro/papain-like protease Protein (SAR-VE1PL)
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.
Please remember our product information: SARS PLpro/papain-like protease Protein (SAR-VE1PL) catalog number: SAR-VE1PL KACTUS Biosystems