SAPANISERTIB (TAK-228) (MLN0128)

Background Information:

Sapanisertib (TAK-228) (MLN0128) is a potent, selective, orally
bioavailable and ATP-competitive mTORC1/C2 inhibitor with an IC50 at low
nM, currently in clinical trials.

APIM050236: SAPANISERTIB (TAK-228) (MLN0128)

CAS No.: 1224844-38-5.
Molecular Formula: C₁₅H₁₅N₇O.
Molecular Weight: 309.3.
Purity: >99.5% (HPLC at 215 and 254 nm).
QC: HPLC-MS, ¹HNMR, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.