PSMA/FOLH1 Rabbit mAb (A22211)
$148.00 – $548.00
Abclonal PSMA/FOLH1 Rabbit mAb (Catalog Number: A22211) encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family.
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| Catalog No. | A22211 |
|---|---|
| Product Name | PSMA/FOLH1 Rabbit mAb (A22211) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | PSM; FGCP; FOLH; GCP2; PSMA; mGCP; GCPII; NAALAD1 |
| Gene Name | FOLH1 |
| Protein Name | FOLH1 |
| Uniprot/Swissprot ID | Q04609 |
| Entrez GeneID | 2346 |
| Clone | ARC56327 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | WB, IHC-P |
| Reactivity | Human, Mouse |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A22211: PSMA/FOLH1 Rabbit mAb
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
Immunogen Information about PSMA/FOLH1 Rabbit mAb (A22211)
Immunogen：A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PSMA/FOLH1 (NP_004467.1).
Sequence：TNITPKHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPG
Gene ID：2346
Swiss prot：Q04609
Synonyms：PSM; FGCP; FOLH; GCP2; PSMA; mGCP; GCPII; NAALAD1; PSMA/FOLH1
Calculated MW：84kDa
Observed MW：100kDa
Images of PSMA/FOLH1 Rabbit mAb (A22211)
Western blot analysis of LNCaP, using PSMA/FOLH1 antibody (A22211) at1:30000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.
Immunohistochemistry analysis of paraffin-embedded human prostate cancer using PSMA/FOLH1 Rabbit mAb (A22211) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Please remember our product information: PSMA/FOLH1 Rabbit mAb (Catalog Number: A22211) Abclonal
Additional information
| Ship from Country | USA |
|---|---|
| Size | 20 ul, 100 ul, 200 ul, 50 ul |