PMEL Rabbit mAb (A23684)
$148.00 – $548.00
Abclonal PMEL Rabbit mAb (Catalog Number: A23684) encodes a melanocyte-specific type I transmembrane glycoprotein.
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| Catalog No. | A23684 |
|---|---|
| Product Name | PMEL Rabbit mAb (A23684) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | P1; SI; SIL; ME20; P100; SILV; HMB45; ME20M; gp100; HMB-45; ME20-M; PMEL17; D12S53E |
| Gene Name | PMEL |
| Protein Name | PMEL |
| Uniprot/Swissprot ID | P40967 |
| Gene ID | 6490 |
| Clone | ARC59527 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A23684: PMEL Rabbit mAb
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
Immunogen Information about PMEL Rabbit mAb (A23684)
Immunogen：Recombinant protein of human PMEL
Sequence：info@abclonal.com
Gene ID：6490
Swiss prot：P40967
Synonyms：P1; SI; SIL; ME20; P100; SILV; HMB45; ME20M; gp100; HMB-45; ME20-M; PMEL17; D12S53E; PMEL
Calculated MW：70kDa
Observed MW：100kDa
Images of PMEL Rabbit mAb (A23684)
Western blot analysis of various lysates, using PMEL Rabbit mAb (A23684) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.
Immunohistochemistry analysis of paraffin-embedded Human malignant melanoma using PMEL Rabbit mAb (A23684) at dilution of 1:1000 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Please remember our product information: PMEL Rabbit mAb (Catalog Number: A23684) Abclonal
