PF-8380

PF-8380

$110.00$720.00

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$110.00$720.00

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SKU: APIM050274
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Description

Background Information:

PF-8380 is an orally bioavailable, potent and competitive inhibitor
of autotaxin (IC = 2.8 nM in enzyme assay; 101 nM in human whole blood).
It directly inhibits autotaxin activity, modulating lysophosphatidic
acid (LPA) levels in vivo and in vitro, and reduces LPA levels both in
plasma and at site of inflammation.

APIM050274: PF-8380

CAS No.: 1144035-53-9.
Molecular Formula: C22H21Cl2N3O5.
Molecular Weight: 478.3 (or refer to Certificate of Analysis, batch-specific).
Purity: >99% by HPLC (214 and 254 nm).
QC: HPLC, NMR and Quantitative Elemental Analysis Report.
Solubility: Refer to Certificate of Analysis.
Storage: Refer to Certificate of Analysis.

Additional information

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USA

Size

10 mg, 100 mg, 200 mg, 50 mg

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