PALBOCICLIB (PD-0332991) (ISETHIONATE SALT)

Background Information:

A potent and highly selective cyclindependent kinase 4 and 6 (CDK
4/6) with IC50 at 11 and 16 nM, respectively. Palbociclib Isethionate
salt is the clinical formulation format in clinical trials.

APIM050218: PALBOCICLIB (PD-0332991) (ISETHIONATE SALT)

CAS No.: 827022-33-3.
Molecular Formula: C₂₄H₂₉N₇O₂ ?1.2 C₂H₆O₄S?0.5H₂O.
Molecular Weight: 607.4.
Purity: >99% (HPLC at 214 and 254 nm).
QC: HPLC, MS, ¹HNMR.
Solubility: Soluble in DMSO, Ethanol and Water.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.