NVP-AUY922

Background Information:

A potent and specific inhibitor of heat shock protein Hsp90a/b with IC50 of 13 and 21 nM, respectively.

Reference:

1. Brough, P. A., et al, 4,5-diarylisoxazole Hsp90 chaperone
inhibitors: potential therapeutic agents for the treatment of cancer, J.
Med. Chem, 2008, 51 (2), 196–218.

APIM050351: NVP-AUY922

CAS No.: 747412-49-3.
Molecular Formula: C₂₆H₃₁N₃O_5.
Molecular Weight: 465.54.
Purity: 99% (HPLC at 214 and 254 nm).
QC: LC/MS, ¹HNMR.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.