Mouse ANXA2 Protein (ANX-ME102)
$243.00 – $810.00
KACTUS Biosystems Mouse ANXA2 Protein (ANX-ME102) (catalog No. ANX-ME102) is expressed from E.coli with His tag at the N-Terminus.It contains Ser2-Asp339.
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| Catalog No. | ANX-ME102 |
|---|---|
| Product Name | Mouse ANXA2 Protein (ANX-ME102) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | Chromobindin-8; Lipocortin II; PAP-IV; ANX2; ANX2L4; CAL1H; LPC2D; ANXA2; Annexin A2; Annexin II; LIP2PAP-IV; LPC2D; LPC2DP36; p36 |
| Species | Mouse |
| Source | E.coli |
| Accession | P07356 |
| Product Tag | N-His |
| Biotinylated | no |
| Exact Sequence | Ser2-Asp339 |
| Molecular Weight | The protein has a predicted MW of 39.6 kDa same as Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in 20mM MES, 150mM NaCl, 200mM L-arginine, 5mM DTT (pH 5.5). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 20mM MES, 150mM NaCl, 200mM L-arginine, 5mM DTT (pH 5.5). |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
ANX-ME102: Mouse ANXA2 Protein (ANX-ME102)
ANXA2, highly expressed in invasive breast cancer cells, is closely related with poor prognosis, and acts as a molecular switch to EGFR activation. ANXA2 expression is inversely correlated with cell sensitivity to gefitinib. Knockdown of ANXA2 expression in MDA-MB-231 cells increased the gefitinib induced cell death. When ANXA2 was overexpressed in MCF7 cells, the gefitinib induced cell death was decreased. Furthermore, the phosphorylation of ANXA2 at Tyr23 is negatively correlated with the sensitivity of TNBC to gefitinib.
Please remember our product information: Mouse ANXA2 Protein (ANX-ME102) catalog number: ANX-ME102 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |