LBH-589

Background Information:

A potent, synthetic inhibitor of histone deacetylase (HDAC).

Reference:

1. Revill, P., et al.; Panobinostat, Drugs of the Future, 32(4), 315, 2007.
2. Dokmananovic, M., et al.; Histone Deacetylase Inhibitors: Overview
and Perspectives, Molecular Cancer Research, 5, 981, Oct. 1, 2007.

APIM050337: LBH-589

CAS No.: 404950-80-7.
Molecular Formula: C₂₁H₂₃N₃O_2.
Molecular Weight: 349.4.
Purity: > 99% (HPLC).
QC: ¹HNMR, HPLC.
Solubility: Soluble in DMSO, water with 1 eq of acid.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.