KPNB1 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

KPNB1 Rabbit mAb

$148.00$548.00

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$148.00$548.00

IMB1; IPO1; IPOB; Impnb; NTF97

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SKU: A23235
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Catalog No. A23235
Product NameKPNB1 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms IMB1; IPO1; IPOB; Impnb; NTF97
Gene Name KPNB1
Protein Name KPNB1
Uniprot/Swissprot ID Q14974
Entrez GeneID 3837
Clone ARC59625
Clonality Monoclonal
Source/Host Rabbit
Applications WB, IHC-P
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene.

Additional information

Ship from Country

USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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