Human Factor XI Protein (FXI-HM101)
$310.50 – $1,035.00
KACTUS Biosystems Human Factor XI Protein (FXI-HM101) (catalog No. FXI-HM101) is expressed from HEK293 with His tag at the C-Terminus.It contains Glu19-Val625.
- Details & Specifications
- References
| Catalog No. | FXI-HM101 |
|---|---|
| Product Name | Human Factor XI Protein (FXI-HM101) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | Coagulation factor XI; FXI; PTA; F11 |
| Species | Human |
| Source | HEK293 |
| Accession | P03951-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Glu19-Val625 |
| Molecular Weight | The protein has a predicted MW of 69.1 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in 25mM HEPES, 150mM NaCl (pH 7.5). |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
FXI-HM101: Human Factor XI Protein (FXI-HM101)
Coagulation factor (F)XI has been described as a component of the early phase of the contact pathway of blood coagulation, acting downstream of factor XII.In contrast to its mild hemostatic activities, FXI is known to play a significant role in thrombosis, as it is a demonstrated independent risk factor for deep vein thrombosis, ischemic stroke, and myocardial infarction. A better understanding of the varied and complex role of FXI in both thrombosis and hemostasis will help to allow better prediction of bleeding risk in FXI-deficient patients and also informing the development of targeted agents to inhibit the thrombotic activities of FXI while preserving hemostasis.
Please remember our product information: Human Factor XI Protein (FXI-HM101) catalog number: FXI-HM101 KACTUS Biosystems