HLA-DRB4 Rabbit mAb
$148.00 – $548.00
DR4; DRB4; HLA-DRB; HLA-DR4B; HLA-DRB4*
- Product Details
- Description
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| Catalog No. | A0439 |
|---|---|
| Product Name | HLA-DRB4 Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | DR4; DRB4; HLA-DRB; HLA-DR4B; HLA-DRB4* |
| Gene Name | HLA-DRB4 |
| Protein Name | HLA-DRB4 |
| Uniprot/Swissprot ID | P13762 |
| Entrez GeneID | 3126 |
| Clone | ARC2505 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | WB |
| Reactivity | Human |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
HLA-DRB4 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. There are multiple pseudogenes of this gene.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 20 ul, 100 ul, 200 ul, 50 ul |