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Description
Background Information:
HA130 is a potent and selective Autotaxin inhibitor (IC50 = 28 nM),
binding and inhibiting Autotaxin reversibly. Displays no activity
against the proteasome, recombinant NPP1 or alkaline phosphatase.
Inhibits ATX-mediated cell migration in an A2058 melanoma cell assay.
Reference:
1. H. M. H. G. Albers, et al, Structure-Based Design of Novel Boronic
Acid-Based Inhibitors of Autotaxin, J. Med. Chem., 2011, 54 (13), pp
4619–4626.
APIM050361: HA130
CAS No.: 1229652-21-4.
Molecular Formula: C24H19BFNO5S.
Molecular Weight: 463.3.
Purity: 99.5% by HPLC at 214 and 254 nm.
QC: HPLC-MS, NMR and Quantitative Elemental Analysis.
Solubility: Refer to Certificate.
Storage: Refer to Certificate.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 10 mg, 100 mg, 200 mg, 50 mg |
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