Fascin/FSCN1 Rabbit mAb (A9566)

Fascin/FSCN1 Rabbit mAb (A9566)

Fascin/FSCN1 Rabbit mAb (A9566)

$148.00$548.00

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$148.00$548.00

Abclonal Fascin/FSCN1 Rabbit mAb (Catalog Number: A9566) encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions.

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Catalog No. A9566
Product NameFascin/FSCN1 Rabbit mAb (A9566)
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms HSN; SNL; p55; FAN1
Gene Name FSCN1
Protein Name FSCN1
Uniprot/Swissprot ID Q16658
Entrez GeneID 6624
Clone ARC1638
Clonality Monoclonal
Source/Host Rabbit
Applications WB, IHC-P
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

A9566: Fascin/FSCN1 Rabbit mAb

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin’s lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Immunogen Information about Fascin/FSCN1 Rabbit mAb (A9566)

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 249-362 of human Fascin/FSCN1 (Q16658).
Sequence:GKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWRDRRITLRASNGKFVTSKKNGQ
Gene ID:6624
Swiss prot:Q16658
Synonyms:HSN; SNL; p55; FAN1; Fascin/FSCN1
Calculated MW:55kDa
Observed MW:54kDa

Images of Fascin/FSCN1 Rabbit mAb (A9566)

Western blot analysis of extracts of various cell lines, using Fascin/FSCN1 Rabbit mAb (A9566) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 1s.

Immunohistochemistry analysis of paraffin-embedded Human anaplastic large cell lymphoma using Fascin/FSCN1 Rabbit mAb (A9566) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Immunohistochemistry analysis of paraffin-embedded Human Hodgkin lymphoma using Fascin/FSCN1 Rabbit mAb (A9566) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Immunohistochemistry analysis of paraffin-embedded human tonsil using Fascin/FSCN1 Rabbit mAb (A9566) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Please remember our product information: Fascin/FSCN1 Rabbit mAb (Catalog Number: A9566) Abclonal

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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