ERG Rabbit mAb (A22748)
$148.00 – $548.00
Abclonal ERG Rabbit mAb (Catalog Number: A22748) encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors.
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| Catalog No. | A22748 |
|---|---|
| Product Name | ERG Rabbit mAb (A22748) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | p55; erg-3 |
| Gene Name | ERG |
| Protein Name | ERG |
| Uniprot/Swissprot ID | P11308 |
| Gene ID | 2078 |
| Clone | ARC58302 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A22748: ERG Rabbit mAb
This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing’s sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined.
Immunogen Information about ERG Rabbit mAb (A22748)
Immunogen：Recombinant protein of human ERG.
Sequence：info@abclonal.com
Gene ID：2078
Swiss prot：P11308
Synonyms：p55; erg-3; ERG
Calculated MW：54kDa
Observed MW：54kDa
Images of ERG Rabbit mAb (A22748)
Western blot analysis of HEL, using ERG antibody (A22748) at 1:2000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit (RM00021).
Exposure time: 90s.
Immunohistochemistry analysis of paraffin-embedded human appendix using ERG Rabbit mAb (A22748) at dilution of 1:600 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded human endometrium cancer using ERG Rabbit mAb (A22748) at dilution of 1:600 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded human tonsil using ERG Rabbit mAb (A22748) at dilution of 1:600 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Please remember our product information: ERG Rabbit mAb (Catalog Number: A22748) Abclonal
