CD32b Unconjugated(110001)
$110.00 – $390.00
Caprico Biotechnologies CD32b Unconjugated catalog number: 110001，The clone 4F5, a mouse monoclonal antibody recognizes anti- FcγRIIb, a cell surface protein also known as CD32b.
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| Catalog No. | 110001 |
|---|---|
| Product Name | CD32b Unconjugated(110001) |
| Supplier Name | Caprico Biotechnologies, Inc. |
| Brand Name | Caprico |
| Accession No. | NC_000001.11 |
| Protein Name | CD32b |
| Uniprot/Swissprot ID | P31994 |
| Entrez GeneID | 2213 |
| Primary/Secondary | Primary |
| Clone | 4F5 |
| Clonality | Monoclonal |
| Source/Host | Mouse |
| Applications | FC |
| Reactivity | Human |
| Immunogen | Recombinant human FcγRIIb/c (CD32b) extracellular domain |
| Form Of Antibody | PBS pH 7.2, 0.1% (w/v) BSA, 0.09% (w/v) sodium azide |
| Conjugate | Unconjugated |
| Purity | >95% |
| Stability & Storage | 2-8oC |
| Note | Products will be shipped from the warehouse in Georgia. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5123 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card. |
Description
110001：CD32b Unconjugated(110001)
The clone 4F5, a mouse monoclonal antibody recognizes anti- FcγRIIb, a cell surface protein also known as CD32b. FcγRII has two major isoforms named FcγRIIa and FcγRIIb with high degree of homology. The clone 4F5 selectively reacts with FcγRIIb but not with FcγRIIa. The CD32b antigen is widely expressed on the cell surface of circulating B lymphocytes, monocytes, neutrophils, myeloid dendritic cells (DCs), platelets and at very low levels on plasmacytoid DCs. FcγRs (FcγRI/CD64, FcγRII/CD32, FcγRIII/CD16, and FcγRIV/CD16-2) play important roles in inflammatory cell activation, clearance, presentation of Ag, and maintenance of IgG homeostasis. Published reports claimed that 4F5 partially blocks the ligand-binding of FcRIIb and mediates an inhibitory signal by co-cross-linking FcRIIb with activating FcRs. Clone 4F5 supports study of the expression, regulation, and function of FcγRIIb and may be useful in the area of therapeutic applications where the modulation of FcγRIIb is required.
Please remember our product information: CD32b Unconjugated(110001) catalog number: 110001 Caprico Biotechnologies
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 μg |