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Biotinylated Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43BB)
$472.50 – $1,575.00
KACTUS Biosystems Biotinylated Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43BB) (catalog No. BH7-HM43BB) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly27-Thr461.
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| Catalog No. | BH7-HM43BB |
|---|---|
| Product Name | Biotinylated Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43BB) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | B7-H3; CD276; PSEC0249; 4Ig-B7-H3; UNQ309; PRO352; B7 homolog 3; CD276 |
| Species | Human |
| Source | HEK293 |
| Accession | Q5ZPR3-1 |
| Product Tag | C-His-Avi |
| Biotinylated | yes |
| Exact Sequence | Gly27-Thr461 |
| Molecular Weight | The protein has a predicted MW of 49.5 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
BH7-HM43BB: Biotinylated Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43BB)
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.
Please remember our product information: Biotinylated Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43BB) catalog number: BH7-HM43BB KACTUS Biosystems
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