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Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43B)

Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43B)

Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43B)

$243.00$810.00

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$243.00$810.00

KACTUS Biosystems Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43B) (catalog No. BH7-HM43B) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly27-Thr461.

SKU: BH7-HM43B
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Catalog No. BH7-HM43B
Product NameHuman B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43B)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms B7-H3; CD276; PSEC0249; 4Ig-B7-H3; UNQ309; PRO352; B7 homolog 3; CD276
Species Human
Source HEK293
Accession Q5ZPR3-1
Product Tag C-His-Avi
Biotinylated no
Exact Sequence Gly27-Thr461
Molecular Weight The protein has a predicted MW of 49.5 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

BH7-HM43B: Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43B)

B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

Please remember our product information: Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM43B) catalog number: BH7-HM43B KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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