ARRY-162 (BINIMETINIB, MEK162)
$75.00 – $350.00
SKU: APIM050080
- Product Details
- Description
- Additional information
- More Offers
Description
Background Information:
ARRY-162 is a potent, orally bioavailable and non-ATP competitive inhibitor of MEK1/2 (IC50 = 12 nM ) and cellular pERK (IC50 = 11 nM) , selective against a panel of other 220 kinases (has no activity at 10 uM). It shows ex vivo inhibition of cytokine production such as IL-1, TNF and IL-6. It is currently in clinical trials.
APIM050080: ARRY-162 (BINIMETINIB, MEK162)
CAS No.: 606143-89-9.
Molecular Formula: C17H15BrF2N4O3.
Molecular Weight: 441.23.
Purity: >99.5% (HPLC).
QC: HPLC-MS, 1HNMR and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 mg, 200 mg, 50 mg, 500 mg |
No more offers for this product!
