Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Antibody (Clone:34-1-2S) | PA007564.m2a
$150.00 – $900.00
Recombinant mouse IgG2a isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
- Details & Specifications
- References
| Catalog No. | PA007564.m2a |
|---|---|
| Product Name | In Vivo Grade Recombinant Anti-mouse MHC Class I (H-2Kd, H-2Dd) Monoclonal Antibody (Clone: 34-1-2S), Mouse IgG2a Kappa |
| Data Sheet | 📄 Download Product Data Sheet (PDF) |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | H2-K1, H-2K, H-2K(d), K-f |
| Clone | 34-1-2S. |
| Isotype | Mouse IgG2a kappa. |
| Source/Host | The anti-mouse MHC Class I (H-2Kd, H-2Dd) monoclonal antibody (clone: 34-1-2S) was produced in mammalian cells. |
| Specificity/Sensitivity | The in vivo grade recombinant mouse monoclonal antibody (clone: 34-1-2S) specifically binds to mouse MHC Class I (H-2Kd, H-2Dd). |
| Applications | ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse MHC Class I (H-2Kd, H-2Dd) protein. |
| Form Of Antibody | 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives. |
| Endotoxin | < 1 EU per 1 mg of the protein by the LAL method. |
| Purity | >95% by SDS-PAGE under reducing conditions and HPLC. |
| Shipping | The in vivo grade recombinant anti-mouse MHC Class I (H-2Kd, H-2Dd) monoclonal antibody of clone 34-1-2S is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |
| Note | Recombinant mouse IgG2a isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card. |
Description
PA007564.m2a: In Vivo Grade Recombinant Anti-mouse MHC Class I (H-2Kd, H-2Dd) Monoclonal Antibody (Clone: 34-1-2S), Mouse IgG2a Kappa
Recombinant mouse IgG2a Monoclonal Antibody.
References of Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Monoclonal Antibody (Clone: 34-1-2S)
1. C-reactive protein enhances murine antibody-mediated transfusion-related acute lung injury.
Kapur, R., et al.Blood. 2015 Dec 17;126(25):2747-51. doi: 10.1182/blood-2015-09-672592. PMID: 26453659
“Furthermore, we demonstrated that TRALI induction was due to 34-1-2s binding to its cognate MHC class I antigens on monocytes, activating them to secrete macrophage inflammatory protein-2 (MIP-2), the murine equivalent of human interleukin-8 (IL-8), which was associated with pulmonary neutrophil recruitment. …The mouse monoclonal antibody 34-1-2s (immunoglobulin G2a [IgG2a]) reacts against murine H-2Kd and H-2Dd MHC class I molecules and was purchased from Bio X Cell (West Lebanon, NH). …The monoclonal antibody recognizes a monomorphic region on the MHC class I α-3 domain (independently of MHC/β2 microglobulin association) and also cross-reacts with MHC class I molecules from the b, q, s, and r strains of inbred mice. Isotype control mouse IgG2a was purchased from Bio X Cell. …In the original study, TRALI induction in BALB/c mice injected with 34-1-2s was robust and significant lung damage was observed. …We report here that CRP can synergistically enhance 34-1-2s-induced TRALI induction in BALB/c mice in vivo, suggesting that this acute-phase protein could be a novel therapeutic target to reduce TRALI reactions.”
For more technical references or data sheets regarding the Recombinant Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Monoclonal Antibody (Clone: 34-1-2S) formats, please contact our scientific support team at message@sydlabs.com.
In Vivo Grade Recombinant Anti-mouse MHC Class I (H-2Kd, H-2Dd) Monoclonal Antibody (Clone: 34-1-2S), Mouse IgG2a Kappa from: In Vivo Grade Recombinant Anti-mouse MHC Class I (H-2Kd, H-2Dd) Monoclonal Antibody (Clone: 34-1-2S), Mouse IgG2a Kappa: PA007564.m2a
