Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971) | PA007299.h1Fs

Catalog No.	PA007299.h1Fs
Product Name	Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971) | PA007299.h1Fs
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	cluster of differentiation 22
Clone	NCI m971.
Isotype	Mouse IgG2a kappa.
Source/Host	The recombinant anti-human Siglec-2/CD22 monoclonal antibody (clone: NCI m971) was produced in mammalian cells.
Specificity/Sensitivity	The recombinant NCI m971 antibody specifically binds to the human Siglec-2/CD22 protein.
Applications	Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).
Form Of Antibody	0.2 uM filtered solution, pH 7.4, containing 0.09% sodium azide.
Endotoxin	Less than 1 EU/mg of protein as determined by LAL method.
Purity	>95% by SDS-PAGE under reducing conditions and HPLC.
Shipping	The The NCI m971 antibody is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, 2 to 8°C as supplied. Do not freeze it.
Note	Recombinant mouse IgG2a isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Order Offline	Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card.

Description

PA007299.h1Fs: Non-conjugated Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)

Recombinant Mouse IgG2a Monoclonal Antibody.

Syd Labs provides the following recombinant anti-human Siglec-2/CD22 monoclonal antibodies for flow cytometry:

Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
Biotin Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
FITC Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
APC Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
PE Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
Pacific Blue Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
PerCP Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
PE/Cy5 Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
PE/Cy7 Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
iFluor 488 Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
iFluor 549 Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
iFluor 594 Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
iFluor 647 Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
iFluor 700 Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
APC/Cy7 Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)
PerCP/Cy5.5 Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971)

Background:

The recombinant NCI m971 antibody binds to the human Siglec-2/CD22 protein, a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer’s patches in mice. In mice, it has been shown that CD22 blockade restores homeostatic microglial phagocytosis in aging brains.

Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971) from: Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971): PA007299.h1Fs Syd Labs

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