Anti-Human / Monkey CD40L (CD154) Antibody (Clone:5c8) | PA007566.m2a
$150.00 – $900.00
Recombinant mouse IgG2a isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
- Details & Specifications
- References
| Catalog No. | PA007566.m2a |
|---|---|
| Product Name | In Vivo Grade Recombinant Anti-human/monkey CD40L (CD154) Monoclonal Antibody (Clone: 5c8), Mouse IgG2a Kappa |
| Data Sheet | 📄 Download Product Data Sheet (PDF) |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | CD154, Cd40l, Tnfsf5, Cd40lg, CD40 ligand |
| Clone | 5c8. |
| Isotype | Mouse IgG2a kappa. |
| Source/Host | The anti-human/monkey CD40L (CD154) monoclonal antibody (clone: 5c8) was produced in mammalian cells. |
| Specificity/Sensitivity | The in vivo grade recombinant mouse monoclonal antibody (clone: 5c8) specifically binds to human/monkey CD40L (CD154). |
| Applications | ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human/monkey CD40L (CD154) protein. |
| Form Of Antibody | 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives. |
| Endotoxin | < 1 EU per 1 mg of the protein by the LAL method. |
| Purity | >95% by SDS-PAGE under reducing conditions and HPLC. |
| Shipping | The in vivo grade recombinant anti-human/monkey CD40L (CD154) monoclonal antibody of clone 5c8 is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |
| Note | Recombinant mouse IgG2a isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card. |
Description
PA007566.m2a: In Vivo Grade Recombinant Anti-human/monkey CD40L (CD154) Monoclonal Antibody (Clone: 5c8), Mouse IgG2a Kappa
Recombinant mouse IgG2a Monoclonal Antibody.
References of Anti-Human CD40L (CD154) Monoclonal Antibody (Clone: 5c8)
1. Contributions of direct and indirect alloresponses to chronic rejection of kidney allografts in nonhuman primates.
Nadazdin O, et al.J Immunol. 2011 Nov 1;187(9):4589-97. doi: 10.4049/jimmunol.1003253. PMID: 21957140
“The relative contribution of direct and indirect allorecognition pathways to chronic rejection of allogeneic organ transplants in primates remains unclear. …In this study, we evaluated T and B cell alloresponses in cynomolgus monkeys that had received combined kidney/bone marrow allografts and myeloablative immunosuppressive treatments. …We measured donor-specific direct and indirect T cell responses and alloantibody production in monkeys (n = 5) that did not reject their transplant acutely but developed chronic humoral rejection (CHR) and in tolerant recipients (n = 4) that never displayed signs of CHR. All CHR recipients exhibited high levels of anti-donor Abs and mounted potent direct T cell alloresponses in vitro. …Such direct alloreactivity could be detected for more than 1 y after transplantation. …No indirect alloresponse by T cells and no alloantibody responses were found in any of the tolerant monkeys.”
For more technical references or data sheets regarding the Recombinant Anti-Human CD40L (CD154) Monoclonal Antibody (Clone: 5c8) formats, please contact our scientific support team at message@sydlabs.com.
In Vivo Grade Recombinant Anti-human/monkey CD40L (CD154) Monoclonal Antibody (Clone: 5c8), Mouse IgG2a Kappa from: In Vivo Grade Recombinant Anti-human/monkey CD40L (CD154) Monoclonal Antibody (Clone: 5c8), Mouse IgG2a Kappa: PA007566.m2a
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