ABT-263

ABT-263

$65.00$360.00

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SKU: APIM050005
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Description

Background Information:

ABT-263 (Navitoclax) is a potent, selective and orally bioavailable inhibitor of B-cell lymphoma-2 (BCL-2) family proteins, binding potently to both BCL-2 and BCL-XL with Ki values of <1 nM.

Reference:

1. Tse C et al., ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor. Cancer Res. 2008 May 1;68(9):3421-8.

APIM050005: ABT-263 (NOVITOCLAX)

CAS No.: 923564-51-6
Molecular Formula: C47H55ClF3N5O6S3
Molecular Weight: 974.6
Purity: >99% by HPLC, 100% optical purity (Chiral HPLC)
QC: HPLC-MS, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis
Solubility: DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.

Additional information

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USA

Size

10 mg, 100 mg, 200 mg, 50 mg

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