TUNEL BrightRed Apoptosis Detection Kit A113
$323.00 – $870.00
Vazyme TUNEL BrightRed Apoptosis Detection Kit (A113)：During apoptosis, intracellular specific endonucleases are activated, chromatin DNA is specifically cleaved between nucleosomes, and DNA is degraded into integer multiples of about 180 – 200 bp fragments.
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Description
A113:TUNEL BrightRed Apoptosis Detection Kit
Product Introduction
During apoptosis, intracellular specific endonucleases are activated, chromatin DNA is specifically cleaved between nucleosomes, and DNA is degraded into integer multiples of about 180 – 200 bp fragments. The 3′-hydroxyl (3′-OH) end generated by DNA fragmentation can bind to fluorescein-12-deoxyuridine triphosphate (FITC-12-dUTP) under the action of terminal deoxynu-cleotidyl transferase (TdT). FITC-12-dUTP-labeled DNA can be directly observed by fluorescence microscopy or quantitatively analyzed by flow cytometry to reflect the level of apoptosis. The BrightGreen Labeling Mix contains FITC-12-dUTP and Bright factors. This unique small molecule compound can non-covalently bind to FITC, enhance its stability and amplify its signal, resulting in brighter labeled fluorescence and stronger anti-quanching ability.
Product Advantages
The patented Bright factor makes the fluorescence brighter and the anti-quenching ability stronger;
Label red fluorescence, which is convenient for co-labeling with other green fluorescence such as GFP;
Highly active recombinant TdT enzyme ensures the efficiency of fluorescence incorporation;
Suitable for cell slides, paraffin sections and frozen sections
Storage
Store at -20℃ for up to 12 months; Store BrightRed Labeling Mix at -20℃ in the dark
Please remember our product information: TUNEL BrightRed Apoptosis Detection Kit catalog number: A113 Vazyme.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 rxns, 25 rxns, 50rxns |