TrkA Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

TrkA Rabbit mAb

$148.00$548.00

In stock

$148.00$548.00

MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA

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SKU: A4147 Categories: ,
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Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Catalog No. A4147
Product NameTrkA Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
Gene Name NTRK1
Protein Name NTRK1
Uniprot/Swissprot ID P04629
Gene ID 4914
Clone ARC0906
Clonality Monoclonal
Source/Host Rabbit
Reactivity Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

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